Peri-anal skin, when localized bacterial infection or fungal infection is present, can lead to perianal inflammation. Patients with mild cases mainly show local pain and itching, etc. Serious cases can lead to local skin erosion and ulcer formation. The main treatment for perianal infection is local medication and anti-inflammatory conservative treatment, usually using potassium permanganate solution at a ratio of 1:5000 to the quality of anti-inflammatory treatment, topical Bactrim or erythromycin ointment. If the infection is serious, you need to add oral antibiotics, you can take oral levofloxacin 0.4g once a day. Patients should pay attention to a light diet, keep the stool soft and avoid spicy and irritating food. Patients should avoid drinking alcohol, pay attention to the cleanliness of the anal area after stool, and try to keep the anus dry. If symptoms continue to flare up or tend to worsen after conservative treatment with medicine, patients need to go to the hospital promptly.