Can prosthesis placement lead to rejection? This is probably the most important question for candidates. It is undeniable that artificial prosthetic materials can indeed cause rejection after implantation, but the probability of this happening is very small. Take the two currently most used materials, silicone has the longest history of use, at least 50 to 60 years of rhinoplasty application experience, the probability of allergy or rejection in the true sense of the word is no more than 0.03%. And this data is still a combination of the results of different manufacturers of silicone prosthesis, did not exclude the factors of different manufacturers of products production quality differences. It is important to know that there is a big difference in the process and product quality between regular manufacturers and small manufacturers, excluding these factors, I believe that the incidence of simple allergic reaction or rejection should be even lower. It is true that the incidence of infection or rejection is higher with expanders compared to silicone. This rejection can occur as early as 1 month after surgery or as long as 2-3 years or more after surgery. Researchers have summarized the reasons for this to include poor removal of impurities during the manufacturing process, bacterial retention in the micropores, and rejection of the expanded material itself. Although careful intraoperative treatment with pressure sterilization, soaking, and rinsing may reduce rejection, its incidence is still high. As a result, some doctors tend to be conservative in their use of expanders at this time. In any case, the safety and histocompatibility of these two materials are excellent, and they can be removed in one piece in the event of infection or rejection. Therefore, consumers can use them with confidence. In the event of rejection, the doctor needs to analyze the intensity and characteristics of the rejection. If the rejection is very mild, it can be treated conservatively by fighting infection, keeping the incision sterile and extracting the exudate; if the rejection is more serious, it is better to take out the prosthesis; fight infection and change the medicine to let the local wound heal first, and then replace it with other materials or autologous cartilage to complete the cosmetic surgery in 3~6 months.