Amlodipine benzenesulfonate and amlodipine mesylate are not recommended to be taken at the same time. Amlodipine benzenesulfonate and amlodipine mesylate are calcium channel blockers, which can reduce the entry of extracellular calcium ions into vascular smooth muscle cells and the contraction of resistance vessels, and are mainly used in the treatment of hypertension and angina pectoris. If amlodipine benzenesulfonate and amlodipine mesylate are taken together, it may lead to an overdose of antihypertensive drugs, which may cause excessive dilation of peripheral blood vessels. As a result, more serious symptoms of systemic hypotension may occur, and bradycardia and other discomforts may also occur. Usually, after taking both of these drugs, you may experience fatigue, edema, dizziness, headache and other discomforts. It is contraindicated for those who are allergic to the components of the drug and those with severe hypotension. Liver and kidney function and blood pressure should be monitored during the course of taking the drug, and pregnant and lactating women should use the drug under the supervision of a doctor. All of the above medications should be used under the guidance of a doctor, avoid self-medication to avoid adverse consequences.