In general, cirrhosis spleen thickness of 60 millimeters already belongs to the serious situation. Clinically, many patients with liver cirrhosis have combined spleen enlargement, generally the spleen enlargement is caused by the increase of blood vessel pressure after cirrhosis portal hypertension, resulting in splenic stasis. And cirrhosis spleen thickness of 60 millimeters, indicating that cirrhosis patients have already appeared splenomegaly, in the loss of compensatory stage, the loss of compensatory stage of the patient may cause portal hypertension. Meanwhile, it is also necessary to analyze the patient’s blood routine test results. If there is no drop in leukocytes and platelets in the routine blood test, and there is no hypersplenism, the treatment of cirrhosis is usually still the main focus. If there is a sharp decline in white blood cells and platelets, and the phenomenon of hypersplenism occurs, then splenectomy may be required for treatment. Therefore, if the patient has cirrhosis with spleen thickness of 60 mm, he should go to the hospital for relevant examination to understand the specific condition and actively cooperate with the treatment under the guidance of professional physicians.