What does non-uniform fatty liver mean?

A non-uniform fatty liver is an uneven accumulation of fat within the liver cells, occurring in one lobe or one part of the liver cells without causing fatty infiltration of all liver cells. On ultrasound it shows hepatic echogenicity that is heterogeneous, with some echogenicity being hypoechoic and some echogenicity being enhanced or normal, and on CT the density of the liver is also heterogeneous. Non-uniform fatty liver differs from diffuse fatty liver because the area of hepatocytes infiltrated by fat is not large and does not reach the total fatty infiltration of hepatocytes. Therefore, the lesions are usually not very serious and can usually be completely reversed and restored to normal with exercise, diet control and, if necessary, liver-protective drugs because of severe liver function damage. However, if non-uniform fatty liver is not controlled and steatosis continues to strengthen, it can lead to diffuse fatty liver and even steatohepatitis and fatty cirrhosis can occur.