EBV generally refers to human herpesvirus type 4. Human herpesvirus type 4 antibody positivity may be the result of infection with human herpesvirus type 4 or previous infection with human herpesvirus type 4. There is a link between EBV infection and nasopharyngeal carcinoma development, which needs to be paid attention to and timely consultation. Human herpesvirus type 4 antibodies can be categorized into VCA-IgM, VCA-IgG, VCA-IgA, EBNA-IgG, EBNA-IgA. 1. VCA-IgM: If a child is positive for VCA-IgM, it is most likely to suggest that the patient has a primary EB infection, which may be due to the development of the disease to the acute stage of infection. 2. VCA-IgG: If the child is positive for VCA-IgG, it suggests that the child has been infected with EBV and may be positive for life, or may be in the early stages of asymptomatic infection. 3. VCA-IgA: If the child is positive for VCA-IgA, it may suggest that the child has recently been infected with EBV, and if the child continues to be positive for this antibody, it means that the chance of nasopharyngeal cancer is relatively high. 4. EBNA-IgG: EBNA-IgG is positive, which may be due to the EBV is in the stage of active viral proliferation, or recently infected with EBV. 5. EBNA-IgA: EBNA-IgA is positive, and long-term positivity is associated with nasopharyngeal carcinogenesis, and is more relevant than VCA-IgA. It is recommended that the presence of positive human herpesvirus type 4 antibodies requires prompt medical attention, and the doctor will choose the appropriate measures for treatment according to the type of human herpesvirus type 4 antibodies.