Nucleic acid testing after people take cold medications (e.g., acetaminophen, ibuprofen, etc.) can have an effect on the nucleic acid test results, but does not affect the negative or positive test results. Related reports indicate a decrease in positive values, but are inconclusive. It is recommended that people undergo nucleic acid testing under the supervision of a physician. Cold remedies do not affect the results of nucleic acid tests, but they do attack the virus, and the amount of virus in the test results may decrease. Nucleic acid tests can be performed normally after taking cold medicines. Cold remedies do not kill the nucleic acids of novel coronaviruses, and health workers do not investigate whether cold remedies have been taken before collecting nucleic acids. Nucleic acid testing is one of the most important ways to detect positive infections as part of a universal screening program.