Hemodialysis brain is an important means of life support for uremic patients, but hemodialysis also has its associated side effects. Side effects that often occur in patients in the early stages of dialysis: 1. Dialysis imbalance syndrome, which is caused by the existence of a significant gradient difference between the patient’s plasma osmolarity and the osmolarity of the brain, resulting in intracranial edema and high pressure causing nausea, vomiting, dizziness, and headache. 2. Patients on hemodialysis may develop allergies in the early stages, and some patients with allergies to the dialyzer or dialysis fluid may develop a rash as well as fever, which may cause severe Early side effects may cause muscle spasms. 4, may lead to hypotension or hypertension. 5, will also appear infections, now less common, sometimes infectious hepatitis C, hepatitis B. 6, long-term dialysis patients will appear carpal tunnel syndrome, or bone chronic osteoarthropathy and other manifestations of this dialysis-related amyloidosis. 7, hemodialysis patients will also appear anemia or nutritional deficiencies. Patients on hemodialysis may also develop anemia or malnutrition.8 Heart problems, such as heart failure, arrhythmia, or vascular calcification, may occur as complications.