The normal value of total cholesterol in fasting blood test for adults is usually below 5.2mmol/L. Therefore, total cholesterol 5.48mmol/L is usually mildly elevated, usually without obvious conscious symptoms, and needs to be clarified by medical examination. The common causes include improper diet, liver cell damage, familial hypercholesterolemia, nephrotic syndrome, etc. It is recommended to seek medical attention in a timely manner and treat the cause according to the relevant examination. 1. Improper diet: A large intake of foods containing high cholesterol, such as animal offal, etc., in a short period of time may cause the total cholesterol to rise to 5.48mmol/L. Usually there are no uncomfortable symptoms and no special treatment is needed. It can be effectively lowered by diet control, avoid eating too much high-fat food and strengthen physical exercise. 2. Damage to liver cells: When liver cells are damaged, such as mild hepatitis, abnormal liver function occurs, bile excretion is blocked and cholesterol esterification is impaired, which may lead to elevation of total cholesterol to 5.48mmol/L. It usually shows symptoms such as skin yellowing and mild ascites, Symptoms such as skin yellowing, mild ascites, etc. It is recommended to seek medical advice and give liver-protective treatment. Commonly used liver-protective drugs include silymarin capsules, etc.; 3. Familial hypercholesterolemia: It is a familial genetic disease with congenital genetic defects leading to long-term cholesterol metabolism disorder. Generally, it can be manifested as mild palpitations and other manifestations, so you can take oral atorvastatin calcium tablets and other drugs as prescribed by the doctor, and you should also eat fruits and vegetables in moderation, which are more beneficial to reduce the total cholesterol in blood; 4. It is usually recommended to seek medical advice and treat the primary disease with medications such as Flavin Capsules as prescribed by the doctor.