Diabetic patients with breakfast fasting blood glucose 12mmol / L, after taking glucose-lowering drugs, it is not recommended not to eat, this situation may lead to hypoglycemia, it is recommended that diabetic patients follow the doctor’s instructions to take medication. 1. There are many hypoglycemic drugs that can lead to the risk of hypoglycemia occurring, especially sulfonylureas. 2. Fasting blood glucose 12mmol/L is high, the first step is to clarify whether it is the Sumuje reaction or the dawn phenomenon. Adjust the treatment program under the guidance of the doctor. At the same time daily avoid high cholesterol, high fat, high sugar food, eat more fresh vegetables, pay attention to the regularity of life, not recommended to stay up late. 3. Diabetic patients are not recommended to lower blood sugar through dieting, need to be scientific and reasonable through diet, exercise, drugs, etc. to lower sugar. In short, it is not advisable to take hypoglycemic drugs without eating, and it is recommended to follow the doctor’s instructions to take medication.