At this point in time, a booster shot of the Neocoronavirus vaccine is not expected to cause leukemia. At the current stage, the main types of neocoronavirus vaccines include inactivated neocoronavirus vaccine, adenovirus-vectored vaccine and recombinant protein vaccine. The booster shot is mainly given on top of the primary immunization to ensure that the titer of anti-neocoronavirus antibodies in the body is maintained at a level that can protect against the virus infection. At present, the side effects of the New Crown vaccine mainly include pain, tenderness, redness, swelling, itching and transient fever at the injection site, etc. Generally, no special treatment is required and symptomatic treatment can be provided if necessary. Relatively rare suspected abnormal reactions to vaccination, such as aseptic suppuration, can also occur. There is no relevant data on the sequelae of vaccination for the time being. According to the current clinical response to booster vaccination, the New Crown vaccine booster does not cause leukemia. Scientific vaccination with booster shots helps to reduce the risk of infection with the virus, but there are certain contraindications to booster shots, and it is also necessary to consult a doctor before vaccination.