White spots on hands and feet may be caused by tinea versicolor, vitiligo, and post-inflammatory hypopigmented spots. 1. Tinea versicolor: Tinea versicolor is caused by fungal infections and is prone to occur on the hands and feet, resulting in localized skin damage, such as blisters, vesicles, impregnated whitish, and localized white spots may appear. 2. Vitiligo: Vitiligo is an acquired skin and mucous membrane pigmentation loss disease that can occur in any part of the body, but also in the hands and feet, resulting in localized white spots. 3. Post-inflammatory hypopigmented patches: Post-inflammatory hypopigmented white patches are caused by certain inflammatory skin diseases. These skin diseases may affect the production of skin pigment, resulting in localized white spots. In addition to this, idiopathic punctate white spots, simple furfura, malnutrition and sun exposure, unpigmented nevi, anemic nevi, etc., may also lead to white spots on hands and feet. It is recommended to go to the dermatology department of the hospital to clarify the cause.