In type II respiratory failure, low-flow oxygen is usually taken, usually 1-2 L/min. If the patient is on a non-invasive ventilator, the oxygen concentration can be increased appropriately, which can reach 3-5 L/min. When the patient has type II respiratory failure, in addition to oxygen, a non-invasive ventilator is also required. When the patient’s non-invasive ventilator is ineffective, invasive ventilator therapy can also be considered, and at the same time, the treatment should be targeted according to the original cause of respiratory failure. For example, if a patient has type II respiratory failure because of chronic obstructive pulmonary disease, he or she can be treated with anti-infective, expectorant, wheezing and other related drugs. For example, amiloride, ipratropium bromide salbutamol, cefoperazone sodium sulbactam sodium, etc., as well as treatment related to airway opening according to the condition.