Preparation for pregnancy is the key to eugenics, in order to conceive a healthy and lively baby, both spouses need to do some physical conditioning, psychological adjustment, dietary adjustment and so on before pregnancy. If the couple is still infertile after 6 months of preparation for pregnancy after adjusting in all aspects, it is recommended to visit the fertility center for a preconception examination for both parties. First of all, it is necessary to inquire about the medical history to understand the time of infertility, age of marriage, health status, sexual life, whether there is contraception, focusing on understanding whether there is inflammation, tuberculosis, especially tuberculosis of the reproductive system, and to understand the situation of menstruation as well as the history of marriage and childbearing, in which menstruation and whether there are previous pregnancies, the number of pregnancies, and whether there are ectopic pregnancies and other conditions must be understood clearly. Secondly, both men and women need to do auxiliary examination, the woman: reproductive hormone 6, thyroid function, 25-OH-VD, insulin, gynecological ultrasound, cervical TCT, HPV, chlamydia, leukorrhea routine, through these tests to understand the woman’s ovarian function and metabolic problems. Male partner: check semen routine, plus sperm DNA fragmentation if necessary. The above is the basic preconception examination for both men and women, for young patients, if there is no abnormality in the basic examination, you can continue to try to conceive, and if necessary, consider follicle monitoring to guide coitus, if follicle monitoring for half a year is still not pregnant, it is recommended to check the tubal imaging to make clear whether the tubes are clear bilaterally. Then according to the tubal condition, decide the next step of treatment. For advanced age, especially those with declining ovarian function, active intervention is based on the specific situation. If there are abnormalities in the basic tests, it is recommended that the abnormal tests be pre-treated first, for example, certain metabolic indexes are abnormal, and pre-treatment in advance is very necessary for successful preparation for pregnancy.