OBJECTIVE: To apply artificial dermis graft and autologous thin-section skin slice to repair open trauma of bone outgrowth in the lower extremity. METHODS: The patients were 11 inpatients from April 2006 to September 2008, 8 males and 3 females, with an average age of 34.6±16.1 (years), and there were 13 traumatic traumas of different degrees of bone exposure in the lower extremity with or without periosteal defects, with a maximum bone exposure area of 3.3×22 cm2; 11 traumatic traumas were combined with different degrees of traumatic infection. The original causes of injury were: plate exposure after internal fixation of the fracture plate, extensive skin exfoliation injury, chronic apposed bone scar ulcers, exposed bone trauma from electrical burns, and skin necrosis from chemical burns. The surgical method was to expand the bone grafting artificial dermis in the first stage, and after the exposed bone surface was covered by dermatoid tissue in 2-6 weeks, the autologous thin section of skin was transplanted in the second stage. Results: 11 cases had good coverage of the exposed bone surface, good healing and plump appearance after skin grafting, and minor damage to the donor area; the interval between the two surgical stages was 19.3±5.2 (days); two cases failed due to infection, one case was an open joint wound and one case was a bone infected wound. At the follow-up of 1-19 months, the wounds healed well, with no obvious adhesions between the dermis and the substrate and satisfactory color appearance. Conclusion: The application of artificial dermis provides a new method for the repair of bone exposed wounds.