Natural antibiotics include quinolone alkaloids, baicalin, succinic acid, fisetin and so on. 1. Quinolinone alkaloids: they have certain antibacterial activity against Staphylococcus aureus, Escherichia coli and so on. 2. Baicalin: it has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa. 3. Succinic acid: it has obvious inhibitory effect on Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and so on. 4. Fisetin: Fisetin in vitro antibacterial effect on Staphylococcus aureus and Candida albicans is more obvious, in vivo on Staphylococcus aureus also has obvious inhibitory effect. These natural antibiotics can kill or inhibit certain germs, and less harmful to the human body, but also able to prevent the attack of germs, specific recommendations to consult a professional doctor.