Treatment modalities for severe viral hepatitis include antiviral therapy, treatment of complications, and symptomatic treatment. 1. Antiviral treatment: different types of specific viruses, different antiviral drugs, hepatitis A has no targeted antiviral drugs, mainly supportive treatment; hepatitis B and hepatitis D often use entecavir, tenofovir and other drugs to fight against viruses and use interferon treatment; hepatitis C can use asurevir, danoravir and other antiviral; hepatitis E often use ribavirin and other drugs to treat. 2. Treatment of complications: severe viral hepatitis is often associated with hepatic encephalopathy, liver failure, coagulation disorders, etc., which may be fatal in severe cases, so artificial liver support, supplementation of albumin, plasma transfusion, lactulose and other medications can be used. 3. Symptomatic treatment: it is also necessary for patients to have bed rest, reasonable diet, limiting the intake of fat and protein, and enteral nutritional support when necessary. Severe viral hepatitis is a serious disease, it is recommended that patients maintain a good attitude, follow the doctor’s instructions and actively treat to improve the prognosis. Drugs need to be used under the guidance of a professional physician, do not self-medicate.