Calcification of the coronary artery wall is usually seen in older patients or in patients with previous arteritis involving the coronary arteries, mainly due to atherosclerosis. If there is calcification in the outer wall of the coronary artery, there is no need to be overly concerned. If it is caused by calcification of lipids in the inner wall of the coronary artery, it may lead to severe narrowing of the coronary artery, and the patient may present clinically with angina pectoris, which is a manifestation of coronary heart disease. In this case, further application of drugs or even implantation of coronary artery stents is needed for treatment. For calcification of coronary arteries, patients should further improve the ultrasound examination of carotid arteries, vertebral arteries and other parts such as lower limb arteries to clarify whether there is severe calcification or stenosis of key parts of the blood vessels, and if needed, timely treatment with aspirin, statin and other drugs should be used.