Avoid taking enzymes if you have peptic ulcers, high stomach acid, or reflux esophagitis. People who are allergic to enzymes should not take enzymes. Patients with peptic ulcer, reflux esophagitis, and much stomach acid may stimulate gastric acid secretion leading to more gastric acid, which stimulates the ulcerated part of gastric mucosa, aggravating the symptoms of peptic ulcer, and easily aggravating the symptoms of reflux esophagitis. People who are allergic to enzymes should not take enzymes. If an allergic reaction occurs, patients usually show symptoms such as rashes, itching and even breathing difficulties. Enzymes are easily inactivated by high temperature, which will reduce the effect, so don’t dilute it with high temperature water, you can dilute it with low temperature water. Enzymes should not be directly irradiated by sunlight, which will make enzymes inactive. Don’t eat enzymes that are too dark in color, such enzymes may be inferior products, in order to be safe, don’t eat this kind of enzymes. Pay attention to the contraindications and precautions for taking enzymes, and seek medical attention promptly if you have any adverse reactions.