Whether the pancreatic density is serious or not needs to be judged by combining clinical manifestations and etiology, if it is acute pancreatitis, it is more serious and needs active treatment; if there is no clinical manifestation, it is mostly considered to be caused by chronic pancreatitis, which is not serious; if it is pancreatic cancer, it is very serious. 1. Acute pancreatitis: the patient’s imaging examination may show uneven density of pancreas, edema, etc., clinical abdominal pain, amylase elevation and other manifestations, which is more serious and needs active treatment. 2. Chronic pancreatitis: patients also have uneven pancreatic density on imaging, but no acute inflammation, this situation is not serious, but need to identify the cause of the active treatment. 3. Pancreatic cancer: pancreatic cancer can also be manifested as uneven pancreatic density, but there are local occupying manifestations or enlargement, elevated tumor markers and other manifestations, which are very serious and the prognosis of pancreatic cancer is not good. If you find uneven pancreatic density, don’t be overly nervous, combine it with medical history and examination, and actively consult your physician for answers.