VWD is the acronym for vascular hemophilia, and there are two clinical types: hereditary vascular hemophilia and acquired vascular hemophilia, also known as acquired vascular hemophilia. 1. Hereditary vascular hemophilia is an autosomal inherited disease, mostly dominant, characterized by a bleeding tendency that occurs since childhood, prolonged bleeding time, and decreased platelet adhesion; 2. Acquired vascular hemophilia generally occurs on the basis of multiple diseases, and a minority of patients can have no apparent underlying disease. The most prominent feature of this disease is a pronounced bleeding tendency, which is mainly in the skin mucosa and can manifest as nasal bleeding, gum bleeding, petechiae, etc., or bleeding more than once after trauma is also more common, and can develop in both men and women. Some women are eventually diagnosed with vascular hemophilia after puberty due to excessive menstruation or heavy bleeding after childbirth.