The callus is a little painful to walk can be treated by surgical treatment, liquid nitrogen freezing, carbon dioxide laser, and medication. 1. Surgical treatment: soaking feet in hot water for 30 minutes can soften the callus. At this time, under the operation of the doctor, use the blade to remove the callus protruding from the surface of the skin, which can make the local protrusion reduce, and the pain symptom when walking is obviously relieved. 2. Carbon dioxide laser: the pain of callus is usually caused by long-term pressure or friction is more intense, the patient can consult a doctor in time. Under the guidance of doctors, carbon dioxide laser can be used to make it necrotic and detach, so as to relieve the pain symptoms. 3. Drugs: you can follow the doctor’s instructions to choose to use salicylic acid cream to corrode off the hypertrophy and hyperplasia of the site, you can also use Vitamin A cream to accelerate the growth of normal stratum corneum. When the normal stratum corneum grows out, the already thickened stratum corneum will gradually decline. There are many treatments for callus pain, it is recommended to go to a specialized hospital, clarify the cause of the disease and then under the guidance of the doctor.