The causes of pain in the nipple position of men are nipple trauma, mastitis, breast hyperplasia, breast cancer and so on. 1. Nipple trauma: nipple in the external force under the extrusion injury, contusion, etc., easy to cause pain in the nipple area, can be localized hot compresses, at the same time, the external use of mupirocin ointment and other anti-infective treatment, the prognosis is better. 2. Mastitis: men can also occur, manifested in the nipple position of redness, swelling, heat and pain, skin cracks, nipple pressure pain, etc., can be oral cefixime anti-infection, ibuprofen and other therapeutic treatment. 3. Breast hyperplasia: patients with breast hyperplasia will also have pain in the nipple position, which can be treated with tamoxifen citrate tablets, and can be surgically removed in serious cases. 4. Breast cancer: breast cancer patients will also have pain in the nipple position, the treatment is mainly based on surgical excision adjuvant chemotherapy, commonly used drugs are doxorubicin combined with paclitaxel. Men with pain in the nipple position should consult a regular hospital in time for early treatment, so as to avoid delaying the condition and affecting the prognosis.