The enema is usually excreted within 5~60min, the specific time of defecation depends on the purpose of the enema and the number of dosage used, there are three kinds of cases: retained enema, small dosage without retained enema and large dosage without retained enema. 1. Retention enema: the main purpose for sedation, hypnosis and treatment of some intestinal diseases, in order to make the efficacy of better, conducive to the drug more fully absorbed, it is often recommended to retain the enema fluid for more than 60 minutes before defecation. 2. Small-dose non-retention enema: generally applicable to the elderly and frail, pregnant women and children and other groups, the main purpose is to let the enema liquid and feces full contact, so that its softening and lubrication, to facilitate better relief of constipation and reduce the symptoms of abdominal distension, it is recommended to retain the enema liquid for 10-20 minutes before defecation. 3. Large-dose unretained enema: the main purpose is to relieve constipation and discharge flatulence and other symptoms, or high fever for cooling and the need for intestinal cleansing of the group, it is generally recommended to lie down for 5 to 10 minutes before defecation. Enema operation should be operated by health care personnel, do not operate on your own, if the corresponding symptoms after enema fails to relieve or discomfort, it is recommended to immediately reflect to the health care personnel to avoid delays in the condition.