Sleeping foot shaking may be a normal physiological factor, or it may be related to pathologic factors such as hypocalcemia, epilepsy, and restless leg syndrome. 1. Physiological factors: If the patient is subjected to excessive strenuous exercise, it may lead to the accumulation of lactic acid in the muscles of the patient, and cause the legs to be accompanied by symptoms such as soreness and weakness, so the phenomenon of shaky feet in the sleep may occur. 2. Pathological factors: Pathological factors usually include hypocalcemia, epileptic restless legs syndrome and other diseases. (1) Hypocalcemia: If the patient has hypocalcemia, there may be a loss of calcium and a decrease in serum calcium concentration, which may cause an increase in neuromuscular excitability, thus causing the symptoms of shaking feet in sleep. (2) Epilepsy: Epilepsy may lead to abnormal discharges in the patient’s brain, which may cause the patient’s muscles to be out of control, causing them to beat irregularly, which may lead to shaky feet in sleep. (3) Restless Legs Syndrome: The main clinical manifestation is that when going to bed and sleeping at night, the extreme discomfort of both lower limbs forces the patient to keep moving the lower limbs, shaking or walking down to improve the symptoms, leading to serious sleep disorders in the patient. Excluding physiological factors, if the patient appears to sleep with shaking feet, it is recommended to go to the hospital in time to clarify the cause of the disease and carry out the correct treatment.