Some patients with pulmonary tuberculosis also have headache symptoms in the early stage of the disease. As the immunity of the body decreases in the early stage, the body’s immune response will be stronger at this time, and the mucous membrane of the lung tissue will be attacked and a large amount of inflammatory secretions will be exuded. At this time, there will be a large amount of inflammatory factors, which will stimulate the trigeminal nerve and other places, and cause headache symptoms. Therefore, clinically, analgesic drugs, including Yuanhu pain relief pills and ibuprofen, are usually given to relieve the headache, and the combination of anti-tuberculosis drugs is actively regulated.