The main ingredients of Flupirtine Melitrexin Tablets are actually two, which are Flupirtine and Melitrexin, mainly with anti-anxiety and anti-depressant effects, and are mainly used clinically for the treatment of mild to moderate depression and anxiety. When the drug is used, it is best to take it on an empty stomach, as depressive symptoms are usually heavy in the morning and light at night, so it is recommended to take it in the morning on an empty stomach. In addition, because the drug may affect sleep, it is recommended to take the second dose at noon if 2 times/day, and avoid drinking alcohol when taking the drug, because drinking alcohol may enhance the inhibitory effect of alcohol on the central nervous system, which may lead to drowsiness and lower body temperature. It is also possible that the medication may reduce concentration as well as responsiveness, so avoid driving and operating machinery. Patients with depression may have suicidal thoughts or behaviors, and must be closely monitored. Long-term medication requires regular checks of mental status and monitoring of blood cell counts and liver function, which can be done every 6 months.