Lupus anticoagulant is positive for antiphospholipid antibody syndrome, systemic lupus erythematosus, arteriovenous embolism and other diseases, and requires further relevant examinations and targeted treatment. Lupus anticoagulant is a kind of pathological anticoagulant produced by patients’ autoimmunity, and this kind of substance may exist in various autoimmune diseases such as antiphospholipid antibody syndrome, systemic lupus erythematosus and other autoimmune diseases as well as arterial and venous embolism, thrombocytopenia and other diseases, so patients with lupus anticoagulant positive all the time need to further improve autoimmune antibody, blood sedimentation and other auxiliary tests to make a clear diagnosis. In addition, pregnant women with positive lupus anticoagulant should also pay attention to complete the relevant obstetric and gynecological examinations to exclude stillbirth, habitual abortion, intrauterine developmental defects and other problems. After the diagnosis has been made, the patient can receive targeted treatment, such as medication for autoimmune diseases and medication or surgery for arterial and venous embolism. Laboratory test results need to be interpreted by a medical professional, and it is recommended that patients who consistently test positive for lupus anticoagulant go to the rheumatology department of a regular hospital for a detailed consultation.