Symptoms such as pain and vomiting when a urinary stone is shattered are mainly due to spasms in the ureter that involve the nerves. Nausea, vomiting, fever, hematuria and pain are common complications of lithotripsy. The cause of pain and vomiting is mainly due to the irritation of the ureter when the stone is discharged through the ureter, causing spasm of the ureteral mucosa, which leads to the irritation of the visceral nerves, thus causing pain and vomiting. If pain occurs after the stone is crushed, analgesic drugs such as diclofenac sodium can be applied under doctor’s supervision. If the pain is severe, ureteral stenting can be performed if necessary, which can help to fully drain and reduce the pressure in the renal pelvis. Those who vomit can follow the doctor’s instructions to apply metoclopramide, vitamin B6 and other drugs to stop vomiting, but also can drink more water to promote the discharge of stones. When symptoms such as pain and vomiting occur after urinary stone fragmentation, you should consult a doctor in time, and under the guidance of specialists, actively carry out appropriate treatment, which will help to alleviate the uncomfortable symptoms as soon as possible.