Generally, the drug can be reduced and gradually discontinued according to the condition after about 3-6 months of injection of Ixepro, but there are individual differences. Ixepro is mainly used for the treatment of active rheumatoid arthritis, moderate to severe plaque psoriasis, and ankylosing spondylitis. This drug is mostly given by subcutaneous injection and 3-4 days should elapse between each injection. The drug needs to be injected for about 2-4 weeks to take effect and will have a stable effect for 3-6 months. However, due to individual differences, such as absorption ability, severity of the disease and duration of illness, the length of injection will also fluctuate. In addition, patients should go to the rheumatology department of the hospital for detailed examination after six months of medication, and carry out the next treatment planning according to the doctor’s suggestion, and should not increase or decrease the dosage or stop the medication according to personal feeling. In addition, it should be noted that patients suffering from malignant tumor, recent infections, sepsis, active tuberculosis infection, and severe cardiac insufficiency, or patients with severe allergy should not apply this drug, and they should consult their doctors before using the drug, conduct the necessary screening, and follow the medical advice to use the drug reasonably.