Severe deficiency of bone density should be disposed of according to the specific situation and cause. In case of aging degenerative osteoporosis caused by aging, severe deficiency of bone density should be treated with appropriate anti-osteoporosis treatment, including the use of bisphosphonates, which is represented by ibuprofen, and calcitonin treatment, which is commonly used for salmon calcitonin, and estrogen replacement therapy can be used for a short time for menopausal women with severe deficiency of bone density. Elderly patients should pay attention to daily maintenance, health care, avoid injury, strenuous exercise and excessive high workload, and more sunshine, pay attention to a balanced diet, and pay attention to calcium and vitamin D. If the severe deficiency of bone density is secondary to other systemic diseases, such as renal bone disease or digestive system nutrient absorption problems, active treatment should be provided for the primary disease. In case of severe deficiency of bone density secondary to other systemic diseases, such as renal bone disease or digestive system nutritional absorption problems, active treatment should be provided for the primary disease to improve the severe deficiency of bone density caused by other systemic diseases.