Glycosylated hemoglobin and lifespan are the same as the lifespan of red blood cells. Therefore, glycosylated hemoglobin (GHb) reflects the average level of blood glucose in the body 8-12 weeks ago, and has nothing to do with the time of blood draw, the patient and whether fasting or not. Its value expressed as a percentage represents the proportion of the amount of glycosylated hemoglobin to the total amount of hemoglobin, and the normal value is 4-6%. Its clinical significance is as follows: 1. It can help diabetic patients to understand the blood sugar control more comprehensively: the fasting or postprandial blood sugar we usually measure can only reflect the blood sugar level at a certain point in time, and cannot take into account the whole day’s blood sugar, while glycated hemoglobin reflects the average blood sugar of the past 2-3 months, which is the blood sugar of the whole surface, and the combination of the two is more comprehensive in understanding the blood sugar from point to surface. The combination of the two can provide a more comprehensive picture of blood glucose from point to point, so that you will not be blinded by the occasional better immediate blood glucose test result and improve the treatment in time. Therefore, glycosylated hemoglobin is the gold standard for evaluating good or bad blood sugar control. 2. It can help to adjust the glucose-lowering drugs: the normal value of glycosylated hemoglobin is <6%, and for diabetic patients, it is usually controlled below 7%, and for individual people, it should be controlled below 6.5%, and the control standard will be appropriately relaxed for the elderly and other special people. The application of insulin may be required to bring blood sugar down to normal. 3, can help prevent and control diabetes complications: research in recent years found that the level of glycosylated hemoglobin and diabetes complications are closely related, elevated glycosylated hemoglobin indicates that patients with persistent hyperglycemia will have complications such as cardiovascular sclerosis, diabetic nephropathy and cataracts, while lower hemoglobin will reduce the occurrence of these complications, and some studies have shown that for every 1% reduction in glycosylated hemoglobin, the risk of microvascular endpoint events It has been shown that for every 1% reduction in glycated hemoglobin, the risk of microvascular endpoints is reduced by 37% and the risk of cataract by 19%. The risk of myocardial infarction is reduced by 14%, the risk of stroke by 12%, the risk of amputation due to peripheral vascular disease by 43%, and the risk of heart failure by 16%. Also be alert for acute complications such as diabetic ketoacidosis when glycated hemoglobin is significantly elevated. 4, can help the screening of diabetes: there are studies to prove that most of the diabetic patients with higher than normal fasting blood glucose and patients with reduced glucose tolerance have increased glycosylated hemoglobin, so it is believed that glycosylated hemoglobin can also be used as a screening for diabetes, and currently the United States has taken glycosylated hemoglobin testing as one of the diagnostic criteria for diabetes, and with the unification of testing standards, China will also gradually take glycosylated hemoglobin as With the unification of testing standards, China will also gradually use glycated hemoglobin as one of the indicators for diagnosing diabetes. 5.It can help to identify stress hyperglycemia: various stresses such as various traumas, myocardial infarction and cerebrovascular accidents can raise blood sugar, but this hyperglycemia is temporary, therefore, glycosylated hemoglobin will not rise, if combined with diabetes, then glycosylated hemoglobin will also rise. The differentiation between the two is valuable for guiding treatment and judging prognosis.