Osteosarcoma usually requires a visit to an oncologist or orthopedic surgeon. Osteosarcoma is a malignant bone tumor characterized by direct formation of osteoid matrix or bone by sarcoma cells. The disease occurs in adolescents and is most commonly found in the long bones of the extremities, especially the distal femur, proximal tibia, and proximal humerus. The most notable symptom of the disease is pain, which starts as intermittent pain and mild, and progresses to persistent pain and nocturnal pain as the disease progresses. Localized swelling may also occur, and there may be obvious pressure pain when pressed. In addition, there may be systemic symptoms such as fever, emaciation and anemia. When osteosarcoma is suspected, it is necessary to go to oncology or orthopaedics, and undergo relevant examinations, such as X-ray, CT, MRI, laboratory tests, histopathological examination, etc., so as to make a clear diagnosis and receive timely treatment.