The lack of significant changes in corns after cryotherapy may be related to the inappropriate way of cryotherapy. Corns are a kind of inverted cone-shaped keratinous growths formed due to prolonged localized friction or extrusion, and the main treatment methods are cryotherapy, laser therapy, drug therapy and surgery, etc. Among them, cryotherapy is more widely used in clinics due to its ease of use and better effect. Cryotherapy is widely used in the clinic due to its ease of use and good results. The process of treating corns with cryotherapy requires several treatments to achieve the desired effect. After a single cryotherapy, blisters, scabs and shedding phenomenon may appear locally. After a period of interval, cryotherapy should be carried out again until the corns fall off completely before the treatment can be stopped. As the single treatment time is too short, or do not follow the course of cryotherapy, it will affect the recovery of the corns, which may also lead to the corns are still not completely eliminated after the treatment, in a state of no change. In order to achieve the ideal treatment effect, you must choose regular medical institutions for standardized treatment.