HBV-DNA refers to the quantification of hepatitis B virus DNA, which is a hepatitis B related monitoring indicator representing the level of hepatitis B virus in the body. Hepatitis B is a highly prevalent infectious disease. For hepatitis B, a comprehensive assessment of hepatitis B condition should be made by integrating liver function, hepatitis B five items, virus quantification, and hepatobiliary system ultrasound. The hepatitis B virus DNA quantification represents the level of hepatitis B virus, the virus value is more active, the virus quantification is higher, the infectiousness is stronger. The main reason why hepatitis B disease will gradually progress and cirrhosis and liver cancer will occur is because of the hepatitis B virus. If you are in the active stage of hepatitis, you should actively carry out antiviral treatment for hepatitis B. Through antiviral treatment, the hepatitis B virus DNA quantification can be gradually reduced to the point of metastasis, and the disease can be better controlled. Hepatitis B virus quantification is a better indicator to assess the clinical efficacy, the virus quantification is transferred, and the patient is not infectious, and the disease is better controlled.