When comparing Down’s syndrome screening with non-invasive DNA, the results of non-invasive DNA are more accurate. The non-invasive DNA test is significantly more accurate than the Down’s syndrome test. The accuracy of the non-invasive DNA test can reach over 90%, while the accuracy of the Down’s syndrome test can reach 60%. Therefore, if you want to have an accurate test, it is better to have a non-invasive DNA test. However, in general, the procedure for non-invasive DNA is cumbersome and complicated, and Down’s syndrome screening is preferred. If the results of the Down’s syndrome screening test do not pass, and there is a moderate risk or high risk, then further non-invasive DNA testing is required. A non-invasive DNA test can accurately detect the presence of trisomy 21 and trisomy 18, and can indicate other genetic problems. Down’s syndrome screening can only be done between 11-20 weeks and non-invasive DNA can be done for a longer period of time as appropriate.