Elevated very low-density lipoprotein (LDL) cholesterol can be improved by taking statins, cholesterol absorption inhibitors, PCSK9 inhibitors and other drugs. 1. Statins: commonly used are Rosuvastatin, Atorvastatin, etc. They can effectively reduce cholesterol synthesis in the body and significantly slow down atherosclerosis. They can effectively reduce the synthesis of cholesterol in the body and significantly slow down the progress of atherosclerosis and other diseases. Side effects often include diarrhea, dizziness, nausea and other symptoms. 2. Cholesterol absorption inhibitor: Ezetimibe is commonly used, which has the ability to inhibit intestinal absorption of cholesterol from food and bile, thus reducing the level of LDL cholesterol. Side effects include headache and nausea. 3. PCSK9 inhibitor: This drug is a more powerful LDL cholesterol-lowering drug, which has the ability to regulate neuronal apoptosis and lower blood lipids. Side effects include allergy. The above drugs should be taken in accordance with medical advice, if you feel unwell, please consult a doctor in time.