When gangrene occurs in patients with atherosclerotic occlusion of the lower limbs, it means that the indication for surgery has been reached and timely surgical treatment is needed to prevent further aggravation of symptoms. Surgical methods mainly include percutaneous endoluminal angioplasty, endothelial stripping and bypass grafting. 1. Percutaneous endoluminal angioplasty: A balloon catheter can be inserted percutaneously to dilate the narrowed and occluded arterial vessels to restore blood flow, and stent implantation can be performed if necessary to improve the rate of arterial patency in the long term. 2. Endothelial stripping: stripping the endothelium, atherosclerotic plaque and thrombus from the diseased section of the artery, this method is mainly used for patients with short-segment iliac-femoral artery occlusion. 3. Bypass grafting: using artificial blood vessels and autologous veins, bypass surgery is performed at both ends of the occluded arteries. When arteriosclerosis occlusion gangrene of lower limbs occurs, it is necessary to consult a doctor in time, complete relevant examinations and carry out standardized treatment under the guidance of a doctor.