If the foot blisters with pronounced itching, if the foot is unilateral, is deep in the type of blisters, and tends to develop ring-collar flaking after drying, consider tinea pedis as a high possibility. Tinea pedis is caused by a fungal infection with significant itching, and can be treated with topical antifungal medications, such as bifenazole cream with good penetration, along with terbinafine cream, alternating once in the morning and once in the evening, and continuing to give the medication for 1-2 weeks after it gets better. Also, avoiding damp and sweaty feet and paying attention to changing shoes and socks regularly can effectively treat tinea pedis. If the rash is bilateral on the feet and the fungal microscopy is negative, eczema is considered more likely. Eczema can be treated with topical Paregoric Pine cream or Trimethoprim cream, applied topically in small amounts twice a day. Those with intense itching can take oral antihistamines, such as loratadine and cetirizine, and need to avoid moist and sweaty feet.