Generally, the 5-year survival rate of stage IV colon cancer is around 10%, and the specific life expectancy varies individually due to patients’ physique and treatment. Stage IV colon cancer belongs to advanced colon cancer, and its condition is often more serious. Preoperative radiotherapy and targeted drug treatment, followed by second-stage radical surgical resection can improve the chance of surgical resection and prolong the survival period, and some patients have a higher five-year survival rate after regular treatment, and the overall life expectancy of five-year survival rate can reach about 10%. However, there are some patients who are in bad condition and cannot tolerate the surgery, and the colon cancer has undergone distant metastasis and proliferation, so the survival period may be shorter, and they can only survive for 2 to 3 years. Stage IV colon should go to the hospital in time, cooperate with doctors to take treatment, and should pay attention to regular review.