Leprosy terror is a clinical diagnosis of disease terror. Leprosy terror is a neurological disorder characterized by a strong fear of leprosy disease, the cause of which is unknown, and some patients have a timid, shy, dependent, introverted personality. Some patients have been subjected to inappropriate health education or trauma as a trigger. The pathogenesis is not well understood. The disease is generally considered to be an auto-compulsive neurosis. In the lack of knowledge of the disease, inappropriate propaganda, memory of their own behavior, and mental stimulation, trauma-induced psychological behavior abnormalities, the fear of disease as the content of neuropsychiatric symptoms. Skin-related disease terror is called dermatophobia. The common ones are leprosy terror, syphilis terror, scabies terror, ophidrosis terror, etc.. Patients often repeatedly consider how to get this disease because they are afraid of suffering from this disease, there will be a lot of pain, etc., all day long emotional anxiety. The burden of thought is heavy, often repeatedly ask the physician to make unnecessary tests or give preventive treatment measures, not to achieve the purpose. The pestering is endless. Psychological counseling should be the main focus, appropriate application of anti-anxiety drugs such as diazepam and small doses of antidepressants such as clomipramine (chlorpromazine).