Cholesterol crystals in the gallbladder wall are usually caused by the precipitation of cholesterol due to the relative increase in the concentration of cholesterol in bile, which results in the formation of crystals, and are generally associated with irregular meals, high-fat diet, low exercise, chronic cholecystitis, etc. 1. Irregular eating: If you often skip breakfast, the bile stored in the gallbladder can not be stimulated by eating and effectively discharged, which can cause an increase in the concentration of bile, cholesterol for a long time in the gallbladder can appear crystallization. 2. High-fat diet: Long-term high-fat diet will affect the balance of lipid metabolism, which will increase the concentration of cholesterol, and then easily cause cholesterol crystallization. 3. Low physical activity: People with low physical activity will affect the emptying function of the gallbladder, causing bile stasis, which will also cause cholesterol to precipitate and remain on the gallbladder wall. 4. Chronic cholecystitis: when chronic cholecystitis occurs, the wall of the gallbladder will be thickened, and the gallbladder will not be emptied completely after eating, which is also the reason for the formation of cholesterol crystals. Cholesterol crystals on the wall of the gallbladder may also be related to other causes. It is recommended to standardize the treatment under the guidance of a doctor, have regular checkups, and pay attention to diet and exercise.