Patients with symptoms of hidden pain on the left side of the penis root may be caused by trauma, prostatitis, varicocele, etc. According to different reasons, patients can take the appropriate treatment drugs under the guidance of the doctor, including ibuprofen, celecoxib, diclofenac sodium and other drugs. 1. Trauma: When the patient’s penis area is hit by external force or injury, it may cause the symptoms of hidden pain on the left side of the penis root, patients without skin lesions can follow the doctor’s instructions to take painkillers, such as ibuprofen, etc.; patients with skin lesions can be used to use iodine povidone, fusidic acid ointment and other medications to carry out local treatment, to improve the symptoms of pain and so on. 2. Prostatitis: patients with prostatitis causing pain on the left side of the penile root can take antimicrobials as prescribed by the doctor, such as ofloxacin, ampicillin, etc.; non-steroidal anti-inflammatory drugs, such as celecoxib, etc.; alpha-blockers, such as tamsulosin hydrochloride, etc., to alleviate the condition of the treatment. 3. Varicose veins: patients with varicose veins can follow the doctor’s instructions to use hepatic saponin drugs, such as hepatic saponin sodium tablets, etc.; flavonoids, such as flavonoids hydrochloride, epoxyflavonoids, etc.; non-steroidal anti-inflammatory drugs, such as diclofenac sodium, ibuprofen and so on. It is recommended that patients strictly follow the doctor’s instructions for the correct use of medication, do not abuse drugs, pay attention to the observation of drug reactions during treatment, if any abnormalities in a timely manner to seek medical attention.