Smoking is very harmful to the cerebral blood vessels and is a risk factor for cerebral infarction. Smoking can lead to damage to the endothelium of the patient’s cerebral blood vessels, leading to the formation of cerebral atherosclerosis. After the endothelial damage caused by smoking, certain components in the blood, such as platelets, uric acid, lipids, leukocytes and other substances will be deposited under the damaged endothelium, resulting in the formation of atherosclerotic plaques, which will easily lead to narrowing of the patient’s cerebral blood vessels. If the plaque formed after narrowing is unstable, it will lead to the problem of cerebral infarction in the patient when it breaks. If the thrombus does not rupture, with the gradual increase of thrombus, the narrowing of blood vessels, blood flow will lead to the formation of cerebral thrombus, cerebral infarction or cerebral blood vessel rupture, bleeding and the formation of cerebral hemorrhage. Therefore, smoking is harmful to the cerebral blood vessels, patients must pay attention to develop good living habits, to quit smoking.