According to the rules and regulations of blood donation, patients with Hepatitis B minor triple positive are not allowed to donate blood. Hepatitis B minor triple positive patients are also hepatitis B patients, no matter how much viral load, are infectious, after blood donation can make others infected with hepatitis B virus, increase the transmission of hepatitis B virus, so patients with minor triple positive are not allowed to donate blood. Need to do a good job of patient health education, to pay attention to diet, pay attention to rest, appropriate exercise, do not stay up late, 3-6 months for a physical examination, the examination program includes liver function, HBV-DNA, AFP, ultrasound and other tests. If there are symptoms such as fatigue, anorexia, etc., check at any time to ensure that the condition is in a stable state. If there is a change in the condition, it can be detected and dealt with as early as possible and treatment can be given.