Uric acid is a product of purine metabolism, and high uric acid can generally be treated through dietary modification and medication. Uric acid is the end product of purine metabolism, mainly produced by the cellular metabolic decomposition of nucleic acids and other purine compounds and purines in food by the enzyme decomposition. The saturation concentration of uric acid in the body at 37°C is about 420 µmol/L. Above this concentration, urate forms crystals that are deposited in a variety of tissues, including the kidneys and synovial membranes of joints, causing tissue damage. Fasting blood uric acid >420µmol/L on two occasions not on the same day is currently defined as hyperuricemia, and the pathophysiological mechanism for its formation is mainly increased uric acid production and decreased uric acid excretion, which can exist alone or coexist. When the discovery of high uric acid, the treatment needs to rule out the use of drugs such as thiazide diuretics (such as hydrochlorothiazide, etc.) caused by high uric acid, usually need to remove the triggers, stop taking drugs. High uric acid can be treated by diet and medication. 1. Dietary regulation: need to strictly control the total calorie diet, strict abstinence from alcohol and limit the intake of high-purine foods such as animal offal, seafood, etc., and drink a moderate amount of water every day to promote uric acid excretion. 2. Drug therapy: patients can follow the doctor’s instructions to take benzbromarone to promote uric acid excretion, take allopurinol, febuxostat, etc. to inhibit uric acid production. If the discovery of high uric acid, it is recommended that the patient immediately consult a doctor, follow the doctor’s instructions standardized treatment, do not take medication, so as not to cause adverse consequences.