There are many causes of groin pain, and common causes include inguinal lymphadenitis, lymphatic tuberculosis and so on. Clinical treatment should be based on the specific causes. 1. Antibacterial drugs: Bacterial infections in the tissues and organs around the groin can lead to swelling and pain in the lymph nodes in the groin, resulting in lymphadenitis, which requires the administration of antibacterial drugs, such as amoxicillin, cefaclor, levofloxacin and other antibiotics. 2. Anti-tuberculosis drugs: inguinal lymphadenitis may also be tuberculosis lymphadenitis, treatment needs to be given to the combination of anti-tuberculosis drugs, such as common rifampicin, isoniazid, ethambutol and so on. 3. Symptomatic treatment: for lymphadenitis caused by groin pain is more intense, or accompanied by fever, can also be given ibuprofen, diclofenac sodium and other antipyretic drugs. The specific situation needs to go to the hospital, improve the auxiliary examination, clear cause, drugs need to be used under the guidance of a professional physician.