How long can one live with terminal hepatic encephalopathy can not be generalized, through standardized comprehensive treatment, it can avoid progressive development of the disease, improve the quality of life of patients and prolong the survival time of patients. Patients with hepatic encephalopathy can be treated with enemas under the guidance of a doctor, such as the use of lactulose, which can acidify the intestinal tract to reduce the absorption of ammonia, and microecological agents, such as probiotics, prebiotics, etc., which can promote the growth of the beneficial flora in the intestinal tract of the host and inhibit the growth of the harmful flora. Patients with end-stage terminal liver can also undergo surgical treatments such as liver transplantation or artificial liver with the help of doctors according to their own conditions. Patients with end-stage hepatic encephalopathy should accept the treatment with a positive mindset and establish confidence in the treatment in order to achieve a better therapeutic effect.