Stage 3b gastric cancer belongs to middle and late stage, and the tumor of corresponding stage has already caused invasion to surrounding tissues or regional lymph node metastasis, and the clinical treatment plan mainly includes surgery, radiotherapy, targeted therapy and daily care. 1. Surgery: if the corresponding stage tumor can be operated through preoperative treatment, radical resection can be done, which requires gastrectomy and gastrointestinal anastomosis. 2. Radiotherapy: For patients who cannot undergo surgery or to prevent recurrence and metastasis after surgery, radiotherapy is needed for control. 3. Targeted therapy: some patients with gene mutation can be treated with targeted drugs, commonly used drugs include trastuzumab. 4. Nutritional support therapy: gastric cancer patients often show symptoms such as poor appetite and discomfort after eating, accompanied by different degrees of anemia and fatigue, so they need to strengthen nutritional support therapy. 5. Daily care: In the process of treatment and recovery, attention should be paid to strengthening nutrition, mainly supplementing essence protein, avoiding too stimulating food, trying to enhance physical quality and maintaining the quality of survival. Tumor causing obvious symptoms of vomiting blood, blood in stool as well as abdominal pain needs timely medical observation and standardized treatment under the guidance of clinicians.