Drinking alcohol after taking Azithromycin is not recommended. Azithromycin belongs to macrolides, which are mainly metabolized and absorbed through the liver, alcohol can also be metabolized and absorbed from the liver, drinking alcohol after using Azithromycin can affect the metabolic function of the liver, causing damage to the liver and affecting the absorption of Azithromycin. Azithromycin cannot produce toxic reactions with alcohol as quickly as cephalosporins. Azithromycin is not recommended to drink alcohol because of the similarity of metabolism with alcohol, which can easily cause damage to the liver if large amounts of alcohol are consumed or if alcohol is consumed carelessly. Take or inject drugs must pay attention to the metabolism way of drugs, keep in mind the contraindications, avoid taking the compatible drugs to affect the absorption, digestion, or even cause serious chemical reactions and toxic reactions to damage the health. It is important to follow medical advice and seek medical attention in the event of adverse reactions or allergic reactions.